جستجوی ارتباط آنتی ژنهای سیستم HLA با UPJO مادرزادی

ABSTRACT: Our primary goal in this study was to find if there is a meaningful correlation between HLA system and congenital UPJO and whether it is possible to use HLA system as a diagnosis marker in congenital UPJO. In this study, 30 patients whose congenital UPJO were confirmed by imaging, underwent HLA typing . The number of the control group who were all kidney donors was two times more than the patients group. The majority of these patients (30 percent) were 30-39 years old and 55 percent of patients were females and 55 percent were males. The most common presentation was flank pain. Statistical calculation indiciates meaningful correlation (P value = 0.05) between congenital UPJO and HLA-A30 -B7 -CW4. It seems that more studies are needed to find which HLA antigens have meaningful correlation with congenital UPJO and whether HLA system could be a diagnostic marker in congenital UPJO or not.